Needles in haystacks: identifying specific peptide antigens for T cells
Identifieur interne : 003E65 ( Main/Exploration ); précédent : 003E64; suivant : 003E66Needles in haystacks: identifying specific peptide antigens for T cells
Auteurs : Nilabh Shastri [États-Unis]Source :
- Current Opinion in Immunology [ 0952-7915 ] ; 1996.
English descriptors
- Teeft :
- Activation assay, Activation assays, Amino acid sequence, Antigen, Antigen processing, Antigen source, Antigenic, Antigenic activity, Antigenic peptide, Antigenic peptides, Apc, Assay, Autologous cytolytic, Biochemical purification, Boon, Cell surface, Cryptic translation, Cytolytic, Donor proteins, Efficient expression, Endogenous, Endogenous pathway, Exogenous, Exogenous stimulation assays, Gene, Gene coding, Gene encoding, Gene products, Genes coding, Human melanoma, Intracellular proteins, Invariant chain, Ligand, Lymphocyte, Mass spectrometry, Melanoma, Melanoma cells, Molecule, Native proteins, Normal genes, Pathway, Peptide, Peptide antigens, Peptide purification, Proc natl acad, Protein antigens, Protein purification, Purification, Quantitative measurements, Shastri, Single activation assays, Small number, Smcy protein, Source tissue, Tumor cells, Unique peptides, Unknown antigens.
Abstract
Abstract: The antigen receptors of T cells are engaged by unique peptides displayed by MHC molecules on the antigen-presenting cell surface. These rare peptides can now be distinguished among the thousands normally bound to MHC molecules. Knowledge of the antigenic peptides and their donor proteins is suggesting potential targets for immunotherapy and providing insights into the cellular mechanisms that generate the peptide-MHC complexes.
Url:
DOI: 10.1016/S0952-7915(96)80067-7
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000E58
- to stream Istex, to step Curation: 000E58
- to stream Istex, to step Checkpoint: 001601
- to stream Main, to step Merge: 003F20
- to stream Main, to step Curation: 003E65
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>Needles in haystacks: identifying specific peptide antigens for T cells</title><author><name sortKey="Shastri, Nilabh" sort="Shastri, Nilabh" uniqKey="Shastri N" first="Nilabh" last="Shastri">Nilabh Shastri</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:68413AF776234026F7DAAC015B28674CE2B6A655</idno><date when="1996" year="1996">1996</date><idno type="doi">10.1016/S0952-7915(96)80067-7</idno><idno type="url">https://api.istex.fr/ark:/67375/6H6-2KSFQCHJ-0/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000E58</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000E58</idno><idno type="wicri:Area/Istex/Curation">000E58</idno><idno type="wicri:Area/Istex/Checkpoint">001601</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">001601</idno><idno type="wicri:doubleKey">0952-7915:1996:Shastri N:needles:in:haystacks</idno><idno type="wicri:Area/Main/Merge">003F20</idno><idno type="wicri:Area/Main/Curation">003E65</idno><idno type="wicri:Area/Main/Exploration">003E65</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a">Needles in haystacks: identifying specific peptide antigens for T cells</title><author><name sortKey="Shastri, Nilabh" sort="Shastri, Nilabh" uniqKey="Shastri N" first="Nilabh" last="Shastri">Nilabh Shastri</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Division of Immunology, Department of Molecular and Cell Biology, University of California, Berkeley</wicri:cityArea></affiliation></author></analytic><monogr></monogr><series><title level="j">Current Opinion in Immunology</title><title level="j" type="abbrev">COIMMU</title><idno type="ISSN">0952-7915</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1996">1996</date><biblScope unit="volume">8</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="271">271</biblScope><biblScope unit="page" to="277">277</biblScope></imprint><idno type="ISSN">0952-7915</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0952-7915</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Activation assay</term><term>Activation assays</term><term>Amino acid sequence</term><term>Antigen</term><term>Antigen processing</term><term>Antigen source</term><term>Antigenic</term><term>Antigenic activity</term><term>Antigenic peptide</term><term>Antigenic peptides</term><term>Apc</term><term>Assay</term><term>Autologous cytolytic</term><term>Biochemical purification</term><term>Boon</term><term>Cell surface</term><term>Cryptic translation</term><term>Cytolytic</term><term>Donor proteins</term><term>Efficient expression</term><term>Endogenous</term><term>Endogenous pathway</term><term>Exogenous</term><term>Exogenous stimulation assays</term><term>Gene</term><term>Gene coding</term><term>Gene encoding</term><term>Gene products</term><term>Genes coding</term><term>Human melanoma</term><term>Intracellular proteins</term><term>Invariant chain</term><term>Ligand</term><term>Lymphocyte</term><term>Mass spectrometry</term><term>Melanoma</term><term>Melanoma cells</term><term>Molecule</term><term>Native proteins</term><term>Normal genes</term><term>Pathway</term><term>Peptide</term><term>Peptide antigens</term><term>Peptide purification</term><term>Proc natl acad</term><term>Protein antigens</term><term>Protein purification</term><term>Purification</term><term>Quantitative measurements</term><term>Shastri</term><term>Single activation assays</term><term>Small number</term><term>Smcy protein</term><term>Source tissue</term><term>Tumor cells</term><term>Unique peptides</term><term>Unknown antigens</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: The antigen receptors of T cells are engaged by unique peptides displayed by MHC molecules on the antigen-presenting cell surface. These rare peptides can now be distinguished among the thousands normally bound to MHC molecules. Knowledge of the antigenic peptides and their donor proteins is suggesting potential targets for immunotherapy and providing insights into the cellular mechanisms that generate the peptide-MHC complexes.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Californie</li></region></list><tree><country name="États-Unis"><region name="Californie"><name sortKey="Shastri, Nilabh" sort="Shastri, Nilabh" uniqKey="Shastri N" first="Nilabh" last="Shastri">Nilabh Shastri</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003E65 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 003E65 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= MersV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:68413AF776234026F7DAAC015B28674CE2B6A655
|texte= Needles in haystacks: identifying specific peptide antigens for T cells
}}
| This area was generated with Dilib version V0.6.33. |  |